Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-04-05
1996-10-15
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 424425, 514773, 514774, 514777, 514781, 514953, A61F 202, A61K 4736, A61K 4738, A61K 4742
Patent
active
055652107
ABSTRACT:
Heteromorphic sponges are described which have matrix structures with oriented substructures added to facilitate cellular invasion. A sponge may be used as a wound implant by cutting it to the shape of a wound bed and placing therein. The matrix structure provides conduits which assist invasion of the sponge by cells which degrade the sponge and lay down new tissue to replace it. The incorporation of active agents in the matrix and/or substructures enhances wound healing.
REFERENCES:
patent: 4233660 (1990-11-01), Luck et al.
patent: 4320201 (1982-03-01), Berg et al.
patent: 4614794 (1986-09-01), Easton et al.
Collagen Sponge: Theory and Practice of Medical Applications; J. Biomed Mater. Res.; vol. 11, pp. 721-741 (1977), Milos Chvapil.
Design of an Artificial Skin. I. Basic Design Principles; J. Biomed. Res. vol. 14, p. 65-81 (1980), I. V. Yannas and John F. Burke.
Light Nicholas D.
Rosenthal Arthur L.
Watt Paul W.
Azpuru Carlos
Farmer Andrew C.
Johnson & Johnson Medical Inc.
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