Bio-selective electrode probes using tissue slices

Chemistry: electrical and wave energy – Processes and products

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204195B, 204195P, G01N 2746

Patent

active

042160650

ABSTRACT:
A bio-selective potentiometric electrode probe for the determination of amino acid concentrations in aqueous liquids comprising an ammonia gas analytical electrode provided at its tip with a closely adjacent thin layer of a fresh animal tissue containing, as a natural constituent thereof, an enzyme effective to catalyze degradation of the specific amino acid in analysis to either ammonia or to an intermediate compound subject to further degradation to ammonia by an additional enzyme, which ammonia is a function of the amino acid concentration in the liquid.

REFERENCES:
patent: 3098813 (1963-07-01), Beebe et al.
patent: 3575836 (1971-04-01), Sternberg
patent: 3776819 (1973-12-01), Williams
patent: 3966580 (1976-06-01), Janata et al.
patent: 3979274 (1976-09-01), Newman

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