Bio-optical sensors

Image analysis – Image sensing

Reexamination Certificate

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C356S436000

Reexamination Certificate

active

07447385

ABSTRACT:
A bio-optical sensor has a surface provided with an array of sensing pixels and calibration pixels. The sensing and calibration pixels are arranged in an interleaved fashion. The sensing and calibration pixels may be interleaved 1:1, or they may be arranged in interleaved blocks. The image plane receives an analyte and a reagent that reacts with the analyte to produce light. The sensing pixels generate signals as a function of the light produced.

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Eggers et al., A Microchip for Quantitative Detection of Molecules Utilizing Luminescent and Radioisotope Reporter Groups, Biotechniques, Eaton Publishing, Natick, US, vol. 17, No. 3, 1994.

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