Bio compatible and blood compatible materials and methods

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Hair or skin

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623 66, 128156, 128157, 128DIG8, 424DIG13, 424447, 424448, 427 2, 523111, 523112, 523113, 514801, A61F 210, A61F 1300, A61L 1500

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active

047252790

ABSTRACT:
Bio-and blood compatible materials are prepared by treating the surface of a substrate to provide reactive primary or secondary amine groups sites which are activated by treatment with a dialdehyde or arylchloride for coupling to a biological in an amount sufficient to provide compatibility. The use of specific substrates, such as a compliant, and elastic material, such as a fabric-elastomer membrane matrix, results in a product having advantageous qualities as a thermal burn dressing. Detailed procedures and various products are described including gloves and sleeves and tubes with or without adhesive to facilitate formation of sheet materials into various forms and products. The products may have small holes provided therein for the rapid passage of accumulated fluid away from the wound or infusion of liquid materials to the wound site.

REFERENCES:
patent: 2693438 (1954-11-01), Ward
patent: 3457098 (1969-07-01), Leininger
patent: 3639141 (1972-02-01), Dyck
patent: 3846353 (1974-11-01), Grotta
patent: 4001583 (1977-01-01), Barrett
patent: 4034751 (1977-07-01), Hung
patent: 4060081 (1977-11-01), Yannas
patent: 4360972 (1982-11-01), Montgomery
Hall et al., "Artificial Skin", Trans. Amer. Soc. Artif. Inl. Organs; 1966; vol. XII pp. 340-343.

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