Bio-artificial organ using microencapsulated enzymes

Surgery – Controlled release therapeutic device or system – Osmotic or diffusion pumped device or system

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604890, A61M 700

Patent

active

044314280

ABSTRACT:
A bio-artificial organ containing a biochemically active matrix is disclosed. The biochemically active matrix includes biochemically active enzyme-containing microcapsules entrapped within a gel matrix. An extracorporeal blood flow can be passed through the organ and over the biochemically active matrix to permit the enzyme to perform its enzymatic function on a substrate in the blood.

REFERENCES:
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4327710 (1982-05-01), De Loach et al.
patent: 4351337 (1982-09-01), Sidman
patent: 4353888 (1982-10-01), Sefton

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