Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1985-09-27
1987-04-14
Foelak, Morton
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530362, 530363, 530380, 530395, 530808, 424 88, 424 89, 435 7, 436514, 436548, 436 86, 436 87, 436819, A61K 3900, G01N 3356
Patent
active
046580220
ABSTRACT:
Binding of a particular protein by an antibody reagent involving denaturation of the protein and use of an antibody reagent specific for binding a linear peptide epitope therein. Denaturation by chemical or physical means effectively exposes or enhances the exposure of the linear peptide epitope for binding by the antibody reagent which is preferably raised against a synthetic peptide immunogen. The technique is particularly useful in performing immunoassays for protein analytes, such as a glycosylated protein, in aqueous test samples.
REFERENCES:
patent: 4247533 (1981-01-01), Cerami et al.
patent: 4423034 (1983-12-01), Nakagawa et al.
patent: 4478744 (1984-10-01), Mezei et al.
Clinical Chemistry, vol. 30, No. 11, Nov. 1984, pp. 1746-1752.
Knowles William J.
Marchesi Vincent T.
Foelak Morton
Molecular Diagnostics, Inc.
Nutter Nathan M.
LandOfFree
Binding of antibody reagents to denatured protein analytes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Binding of antibody reagents to denatured protein analytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Binding of antibody reagents to denatured protein analytes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1786925