Chemistry: analytical and immunological testing – For preexisting immune complex or auto-immune disease – Immune complex
Patent
1991-03-19
1993-06-22
Nucker, Christine M.
Chemistry: analytical and immunological testing
For preexisting immune complex or auto-immune disease
Immune complex
436501, 436509, 436518, 436536, 436538, 436808, 435 71, 435 78, 435975, G01N 33564, G01N 33543
Patent
active
052216284
ABSTRACT:
A method of binding aggregated immunoglobulin or immune complexes comprising contacting them with serum amyloid P component ("SAP"). The invention also comprises methods of using SAP to detect or quantitate immune complexes and to deplete fluids of aggregated immunoglobulin or immune complexes for diagnostic or therapeutic purposes. Also provided is a test kit comprising SAP for detecting or quantitating immune complexes and a device for removing aggregated immunoglobulin or immune complexes from fluids.
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Anderson Byron E.
Brown Marilyn R.
Dubrule Chris
Northwestern University
Nucker Christine M.
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