Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-04-03
2007-04-03
Kemmerer, Elizabeth (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S007210, C435S219000, C435S221000, C530S324000, C530S326000, C530S327000
Reexamination Certificate
active
10662651
ABSTRACT:
The present invention relates to the identification of the molecular binding domains between presenilins and its substrates such as amyloid precursor protein and telencephalin. These binding domains can be efficiently used in drug screening assays to screen for compounds capable of modulating the interaction between presenilins and type I transmembrane proteins. The invention further relates to compounds capable of modulating the interaction.
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Annaert Wim
De Strooper Bart
Emch Gregory S
Kemmerer Elizabeth
TraskBritt
Vlaams Interuniversitair Instituut voor Biotechnologie VZW
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