Binding compounds, immunogenic compounds and peptidomimetics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Reexamination Certificate

active

07863239

ABSTRACT:
The invention provides means and methods for producing compounds suitable for testing for the presence and/or identification of an immunogenic compound and/or a binding compound of interest. Immunogenic compounds and compositions are also herewith provided, as well as peptidomimetics of members of the cystine-knot family.

REFERENCES:
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#Timmerman et al., Rapid and quantitative cyclization of multiple peptide loops onto synthetic scaffolds for structural mimicry of prot6ein surfaces, Chembiochem: A European Journal of Chemical Biology, May 2005, pp. 821-824, vol. 6, No. 5.
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#Timmerman, Mapping of a discontinuous and highly conformational binding site on follicle stimulating hormone subunit-beta (FSH-beta) using domain Scan™ and Matris Scan™ technology, Molecular Diversity, 2004, pp. 61-77, vol. 8, No. 2.
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#Sun et al., The Cysteine-knot Growth Factor Superfamily, Annual Review of Biophysics and Biomolecular Structure, Annual Reviews Inc., Palo Alto, CA, US, 1995, pp. 269-292, vol. 24.
#Vitt et al., Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules, Molecular Endocrinology, Baltimore, MD, US, May 2001, pp. 681-694, vol. 15, No. 5.
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PCT International Search Report, PCT/NL2006/000036, dated May 18, 2006.

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