Binding assays involving formation and detection of light scatte

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435810, 436 36, 436501, 436518, 436525, 436536, 436805, 436808, 436809, G01N 3353, G01N 33537, G01N 2100, G01N 2147

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047270241

ABSTRACT:
A methodology for the detection of an analyte of interest in a fluid sample through the formation, growth, and optical detection of light scattering crystals. The methodology provides for direct assay and competitive binding assay protocols using pairs of specifically binding compositions and novel innovations in crystal growth technology to provide an analytical method which is useful in immunodiagnostic, environmental, and biochemical applications. The methodology and test kit apparatus provides rapid, reproducible, and accurate data and is sensitive for the detection of an analyte of interest present in the nanogram per milliliter range.

REFERENCES:
patent: 3926564 (1975-12-01), Giaever
patent: 4205952 (1980-06-01), Cais
patent: 4380587 (1983-04-01), Koocher
patent: 4480042 (1984-10-01), Craig
patent: 4565790 (1986-01-01), Hemmila
patent: 4581337 (1986-04-01), Frey

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