Binding assays

Details Binding assays Binding assays

2000-08-21

2004-04-27

Nguyen, Bao-Thuy L. (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

C435S007100, C435S006120, C435S007920, C435S007940, C435S287200, C436S525000, C436S526000, C436S805000, C436S806000, C422S082050, C422S068100, C422S082080, C422S063000, C422S066000, C422S067000, C422S051000

Reexamination Certificate

active

06727103

ABSTRACT:

RELATED APPLICATIONS
The present application is related to the following application:
“Molecular Detection Devices and Methods of Forming Same”, Ser. No. 08/846,975, filed Apr. 30, 1997.
The subject matter of the above-listed application is hereby incorporated by reference into the disclosure of the present application.
TECHNICAL FIELD
The present invention relates to molecular detection devices and methods and systems for performing a binding assay therewith.
BACKGROUND OF THE INVENTION
Recent efforts have been directed in developing chips for molecular detection. Of particular interest are DNA chips for sequencing and diagnostic applications. A DNA chip includes an array of chemically-sensitive binding sites having single-stranded DNA probes or like synthetic probes for recognizing respective DNA sequences. The array of binding sites is typically arranged in a rectangular grid.
A sample of single-stranded DNA is applied to the binding sites of the DNA chip. The DNA sample attaches to DNA probes at one or more of the binding sites. The sites at which binding occurs are detected, and one or more molecular structures within the sample are subsequently deduced.
In sequencing applications, a sequence of nucleotide bases within the DNA sample can be determined by detecting which probes have the DNA sample bound thereto. In diagnostic applications, a genomic sample from an individual is screened with respect to a predetermined set of probes to determine if the individual has a disease or a genetic disposition to a disease.


REFERENCES:
patent: 4118280 (1978-10-01), Charles et al.
patent: 5096670 (1992-03-01), Harris et al.
patent: 5139744 (1992-08-01), Kowalski
patent: 5518923 (1996-05-01), Berndt et al.
patent: 5532128 (1996-07-01), Eggers et al.
patent: 5545531 (1996-08-01), Rava et al.
patent: 5565324 (1996-10-01), Still et al.
patent: 5653939 (1997-08-01), Hollis et al.
patent: 5736332 (1998-04-01), Mandecki
www.labfocus.com/biochem/labfeat.htm—Printed Nov. 1996.
www.labfocus.com/abc/STAFEA.htm—Printed Nov. 1996.
www.awaretech.com/Identi-Link.html—Printed Nov. 1996.
www.sanguin.com/M2000.htm—Printed Nov. 1996.
www.sanguin.com/INFORM.htm—Printed Nov. 1996.
www.packardinst.com/m-probe.htm—Printed Nov. 1996.
www.packardinst.com/mp204-bc.htm—Printed Nov. 1996.
Product Description, Gamera Bioscience Personal.

Affiliated with

Also associated with

Rating

Binding assays does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Binding assays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Binding assays will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3256465