Binding assay employing human T2R taste receptors

Details Binding assay employing human T2R taste receptors Binding assay employing human T2R taste receptors

2008-07-08

2008-07-08

Ulm, John D (Department: 1649)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007200, C435S007210, C436S501000

Reexamination Certificate

active

10986871

ABSTRACT:
Newly identified mammalian taste-cell-specific G Protein-Coupled Receptors and the genes encoding said receptors are described. Specifically, T2R taste G Protein-Coupled Receptors that are believed to be involved in bitter taste sensation, and the genes encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular tastant in a mammal are also described, as are methods for generating a novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes.

REFERENCES:
patent: 6383778 (2002-05-01), Zuker et al.
patent: WO 01/18050 (2001-03-01), None
patent: WO 01/77676 (2001-10-01), None
patent: WO 02/16548 (2002-02-01), None
Brenner et al., PNAS 95(6073-6078)1998.
Bowie et al., 1990, Science 247:1306-1310.
Guo-HH et al. PNAS 101(25)9205-9210, 2004.
Alexander et al., Proc. Natl. Acad. Sci. 89(3352-3356)1992.
Hoon et al., Cell 96(541-551)1999.
Chandrashekar et al., Cell 100(703-711)2000.
Database EMBL [online] Oct. 11, 1999, B. Biren et al., “Homo sapiensclone RP11-17E6”, XP002372161 retrieved from EBI Database Accession No. AC011654.
E. Adler et al., “A Novel Family of Mammalian Taste Receptors” Cell, vol. 100, No. 6, p. 693-702 Mar. 17, 2000.
David Smith et al., “Taste Processing: Whetting our Appetites”, Current Biology, vol. 9, No. 12, p. R453-R455, Jun. 17, 1999.
Peter Mombaerts, “Molecular Biology of Odorant Receptors in Vertebrates”, USA Series: Annual Review of Neuroscience (ISSN 0147-006X), 1999, p. 487-509.

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