Binding assay device

Details Binding assay device Binding assay device

1993-11-03

1997-06-24

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

422 56, 435 25, 435 27, 435 28, 435962, 435963, 435970, 435975, 436501, 436514, 436518, 436530, 436810, 436817, G01N 33543, G01N 33558

Patent

active

056416393

ABSTRACT:
A device for performing an enzyme-labelled binding assay comprises an absorbent material and a developing solution containing a substrate for said enzyme, wherein the absorbent material is provided with a plurality of reagent zones including an indicator reagent zone and is capable of transporting the developing solution by capillary action sequentially through the reagent zones, and wherein the indicator reagent zone includes a reagent capable, directly or indirectly, of immobilising an enzyme-labelled reagent in an amount dependent on the assay result, characterized in that the absorbent material includes a reagent that prevents a signal formation except where enzyme-labelled reagent is immobilised at the indicator reagent zone. The absorbent material is suitably in the form of an elongate strip provided with transverse reagent zones. The device is useful for performing immunoassays, including immunometric assays and dual analyte assays.

REFERENCES:
patent: 4690907 (1987-09-01), Hibino et al.
patent: 4837395 (1989-06-01), Leeder et al.
patent: 4857453 (1989-08-01), Ullman et al.
patent: 4861711 (1989-08-01), Friesen et al.
patent: 5104793 (1992-04-01), Buck
Aldrich Chemical Company, Inc, Catalogue, 1990, pp. 491 and 672.
Worthington Enzyme Manual, Worthington Biochemical Corporation, 1972. p. 43 .

Affiliated with

Also associated with

Rating

Binding assay device does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Binding assay device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Binding assay device will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-148443