Chemistry: physical processes – Physical processes – Crystallization
Patent
1977-01-03
1978-02-14
Reese, Robert M.
Chemistry: physical processes
Physical processes
Crystallization
23259, G01N 3106
Patent
active
040736202
ABSTRACT:
Apparatus for performing binder-substrate processing of clinical substances is disclosed. An operating head is provided which includes an array of upwardly opening receptacles each having a closed bottom. A temperature control element is located in the operating head proximate the receptacles. The operating head also includes a manifold having an influx chamber, an efflux chamber and a plurality of hollow prongs emanating from the influx chamber and through the efflux chamber. The prongs extend downwardly into respective of the receptacles to provide fluid communication between the influx chamber and the interior of the receptacles through the prongs. The efflux chamber is in fluid communication with the open ends of the receptacles to drain fluid therefrom. A solid phase binder is located in the bottoms of the respective receptacles, and may be coated on solid phase elements located in the receptacles or on the receptacles themselves. The solid phase binder is immersed in the clinical substances for incubation by the temperature control element. After incubation of the clinical substances, the operating head is inverted. A washing fluid is injected into the influx chamber of the inverted operating head so that the washing fluid flows upwardly through the prongs to wash excess of the clinical substances from the solid phase binder retained in the receptacles. The washing fluid is drained from the operating head through the efflux chamber. A drying fluid is usually injected into the influx chamber of the inverted operating head so that the drying fluid flows upwardly through the prongs and into the receptacles to dry the solid phase binder and incubated clinical substances adhering thereto.
REFERENCES:
patent: 3488156 (1970-01-01), Good et al.
patent: 3525591 (1970-08-01), Jungner et al.
patent: 3622279 (1971-11-01), Moran
Gray Michael J.
Stanton Raymond E.
Gray and Stanton
Reese Robert M.
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