Binder-free orally administrable tablet containing 3-oxygermylpr

Details Binder-free orally administrable tablet containing 3-oxygermylpr Binder-free orally administrable tablet containing 3-oxygermylpr

1992-06-30

1994-01-18

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424464, 514492, A61K 920

Patent

active

052798356

ABSTRACT:
A 3-oxygermylpropionic acid preparation is provided, which activates the action of 3-oxygermylpropionic acid having the general formula:
[(O.sub.1/2).sub.3 GeCH.sub.2 CH.sub.2 COOH]n wherein n=an integer of at least 1 and is readily solubilized and disintegrated in vivo. The present preparation is manufactured by compression-molding at high pressure a composition comprising 3-oxygermylpropionic acid and two or more low-molecular substance of high solubility in water. The low-molecular substances are selected from the group consisting of white sugar, sorbitol, fructose, sucrose, glucose, lactose, mannitol and sodium chloride.

REFERENCES:
patent: 4889715 (1989-12-01), Sawai et al.
patent: 5008416 (1991-04-01), Kurono et al.

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