Binder composition and analytical element having stabilized pero

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 25, 435 28, 435188, 435805, 436810, 436826, 436528, 436535, 422 56, 422 57, G01N 3350

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active

048746924

ABSTRACT:
An analytical element has a peroxidase-labeled ligand analog distributed within a layer comprising from 0.1 to 10.0 g/m.sup.2 of poly(vinyl-alcohol) and from 0.2 to 20.0 g/m.sup.2 of glycerol. The concentration of the glycerol must be greater than 1 times the concentration of poly(vinylalcohol) in the layer. As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine a number of different immunologically reactive analytes, such as digoxin.

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