Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Aftertreated solid synthetic organic polymer
Patent
1995-09-29
2000-08-22
Fay, Zohreh
Drug, bio-affecting and body treating compositions
Designated organic nonactive ingredient containing other...
Aftertreated solid synthetic organic polymer
514 54, 514912, A61K 4700
Patent
active
061073474
ABSTRACT:
Compositions and methods useful for protecting human or animal eye cell layers and tissues exposed to trauma, e.g., during surgery, are disclosed. In one embodiment, the method comprises administering a protective amount of an ophthalmically acceptable aqueous composition containing a first alkali metal and/or alkaline earth metal hyaluronate fraction having a molecular weight of at least about 2 million, for example, in the range of about 2 million to about 4 million, and a second alkali metal and/or alkaline earth metal hyaluronate fraction having a molecular weight of about 200,000 to about 800,000, for example, in the range of about 300,000 to 700,000, to eye cell layers and tissues prior to the exposure to the trauma.
REFERENCES:
patent: 4141973 (1979-02-01), Balazs
patent: 4303676 (1981-12-01), Balazs
patent: 4517295 (1985-05-01), Bracke et al.
patent: 4784990 (1988-11-01), Nimrod et al.
Anterior Segment Surgery with Use of a New Type of Sodium Hyaluronate Preparation IAL, Fruscella et al, 1987.
Patent Abstracts of Japan, vol. 13, No. 487, 1989.
Taverniti, Hyaluronate de sodium . . . , Bull. Mem. Soc. Fr. Ophthalmol., vol. 97, 1986, pp 556-559.
Marchi, Vantaggi derivanti . . . , Ann. Ottaimol. Clin. Ocul., vol. 115, No. 5, 1989, pp 567-571.
MartinDale 1960267 (1989).
Glasser et al, "Protective Effects of Viscous Solutions in Phacoemulsification and Traumatic Lens Implantation",Arch Ophthalmol-vol. 107, Jul. 1989.
Leith et al, Comparison of the properties of AMVISC,.RTM. and Healon.RTM. J Cataract Refract Surg-vol. 13, Sep. 1987.
Soll, et al, "Evaluation and Protection of Corneal Endothelium",AM Intra-Ocular Implant Soc J-vol. 6, Jul. 1980.
Pape et al, "The Use of Sodium Hyaluronate (Healon.sup..RTM.) in Human Anterior Segment Surgery", Ophthalmology, Jul. 1980 vol. 87, No. 7.
Christ F. Richard
Francese James E.
Allergan
Fay Zohreh
Uxa Frank J.
LandOfFree
Bimodal molecular weight hyaluronate formulations and methods fo does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bimodal molecular weight hyaluronate formulations and methods fo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bimodal molecular weight hyaluronate formulations and methods fo will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-581679