Bilirubin-resistant determination of uric acid and cholesterol

Details Bilirubin-resistant determination of uric acid and cholesterol Bilirubin-resistant determination of uric acid and cholesterol

1980-03-24

1981-09-22

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving uric acid

23230B, 23909, 23925, 252408, 422 56, 435 11, 435 28, 435805, G01N 3352, G01N 3392, G01N 3372

Patent

active

042911214

ABSTRACT:
A composition, test device, method of making a test device and process for bilirubin-resistant determination of an analyte selected from uric acid or cholesterol in a fluid sample are disclosed. More particularly, the composition is of the type comprising means responsive to the presence of the particular analyte to be determined in the sample, a phenol and 4-aminophenazone to which resistance to interference by bilirubin is imparted by inclusion therein of reagent means comprising a ferrocyanide ion. The uric acid or cholesterol responsive means is preferably of the type which determines peroxides formed from enzymatic conversion of the analyte. The composition can optionally be incorporated with a carrier to provide a test device.

REFERENCES:
patent: Re29498 (1977-12-01), Meiattini
patent: 4095948 (1978-06-01), Hunziker
patent: 4184921 (1980-01-01), Roeschlav
patent: 4186251 (1980-01-01), Tarbutton
patent: 4247631 (1981-01-01), Nix
patent: 4251629 (1981-02-01), Yamanisi
"Hackh's Chemical Dictionary," J. Grant, ed., 4th Edition, p. 507, McGraw-Hill, New York, 1969.

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