Bile acid derivatives, processes for the preparation thereof and

Details Bile acid derivatives, processes for the preparation thereof and Bile acid derivatives, processes for the preparation thereof and

1990-04-09

1991-10-15

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

552540, 552542, 552551, C07J 900, A61K 31575

Patent

active

050575090

ABSTRACT:
Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carbonanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.

REFERENCES:
patent: 4921848 (1990-05-01), Frigerio et al.

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