Bilateral microinjector pump for freely moving animals in an...

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

Reexamination Certificate

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C604S155000, C417S572000

Reexamination Certificate

active

06475188

ABSTRACT:

BACKGROUND FOR THE INVENTION AND DEVELOPMENT OF THE BILATERAL MICO-INJECTOR PUMP
Procedures in behavioral pharmacology and neuroscience require bilateral intravenous and intra-cerebral micro-injections to be made into freely behaving and moving animals. For example, simultaneous drug administration to discrete populations of neurons within bilaterally paired sub-cortical regions avoids hemisphere-specific effects associated with unilateral injections and increases the chance of detecting the desired response. Also, animals can freely self-administer drugs without the stressful handling of humans. Because fluid swivel systems are not reliable at the volumes required for scientific studies in the fields mentioned above, I substituted an electrical swivel that allows for free movement of the micro-injector pump and the animal to which it is tethered by way of capillary tubing.


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