Bifunctional compound containing amino group and...

Details Bifunctional compound containing amino group and... Bifunctional compound containing amino group and...

2011-06-21

2011-06-21

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

Reexamination Certificate

active

07964752

ABSTRACT:
A bifunctional compound containing an amino group and diaminedithiol ligand and a manufacturing method thereof are revealed, the bifunctional compound includes at least one amino group and a diaminedithiol (N2S2) ligand. The amino groups is for reacting with compounds containing carboxylic acids or halogens while the N2S2ligand binds with technetium or rhenium so as to form an anion complex. The thiol group in the N2S2ligand is protected by a protecting group for prevention of oxidation and easy storage. This protecting group is released easily during complex reactions. Due to the bifunctional property, the compound is applied to preparation of radiopharmaceuticals such as imaging agents and targeted agents.

REFERENCES:
patent: 4279805 (1981-07-01), Ohzeki et al.

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