Bifunctional chelating agents and process for their production

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436536, 436542, 436545, 436804, 436815, 436817, 436824, 530350, 534 14, 556 1, G01N 3353, G01N 33536, G01N 33534

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active

046525190

ABSTRACT:
There are provided bifunctional chelating agents, which are analogues of EDTA, conjugates of same with a variety of haptens and conjugates of such conjugates with haptens with certain metals, forming metal complexes. The metal complexes have a variety of uses, among these various assays for the determination of haptens and macromolecules. There is also provided a process for the production of the above. There are provided radioimmunoassays based on the above conjugates with metal cations.

REFERENCES:
patent: 4320109 (1982-03-01), Wolf et al.
patent: 4432907 (1984-02-01), Wieder et al.
Sundberg et al., J. Med. Chem., 17 (1974), 1304-7.

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