Bifunctional chelating agents

Details Bifunctional chelating agents Bifunctional chelating agents

1994-02-16

1996-01-30

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Isothiocyanate esters

C07C33128

Patent

active

054881269

ABSTRACT:
A new series of bifunctional chelating agents useful for attaching metal ions to proteins, polypeptides and other polymers and methods for their preparation are described. These reagents are unique in their ability to bind a variety of metal ions and to yield a high metal ion concentration per protein molecule. Using these methods polymeric analogs of these bifunctional chelating agents called Starburst ligands can also be obtained. Protein metal chelates thus obtained will have useful radiophysical, chemical, fluorescent, photochemical and magnetic properties suitable for biomedical applications.

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