Bifunctional blocked phosphoramidites useful in making nucleic a

Organic compounds -- part of the class 532-570 series – Organic compounds – Acyclic carbon bonded directly to three benzene rings or to...

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549220, 558185, C07F 924

Patent

active

053591003

ABSTRACT:
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.

REFERENCES:
patent: 4914210 (1990-04-01), Levenson et al.

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