Bicyclopolyazamacrocyclocarboxylic acid complexes for use as con

Details Bicyclopolyazamacrocyclocarboxylic acid complexes for use as con Bicyclopolyazamacrocyclocarboxylic acid complexes for use as con

1993-12-22

1996-01-02

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540472, 5303913, 5303915, 424 934, 424 935, C07F 9652, A61K 31555

Patent

active

054809908

ABSTRACT:
Complexes of bicyclopolyazamacrocyclocarboxylic acid with Gd, Mn or Fe ions are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complexes and conjugates are useful as contrast agents for diagnostic purposes.

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