Bicycloalkyl tricycloalkyl, azabicycloalkyl and azatricycoalkyl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564162, A61K 31165, C07C32100

Patent

active

050195972

ABSTRACT:
The compounds of this invention are bicyclic, tricyclic, azabicyclic and azatricyclic amides represented by the formula: ##STR1## wherein: R.sub.1 and R.sub.2 are the same or different members of the group consisting of halo, phenyl, substituted phenyl and a ##STR2## group wherein n, m and p are independently an integer of from 1 to 8 provided that n+m+p is equal to or less than 10; X is thio, sulfinyl or sulfonyl; Alk is straight or branched chain lower alkylene; R.sub.3 is selected from the group consisting of a bicycloalkylamino, tricycloalkylamino, azabicycloalkyl, azatricycloalkyl, azabicycloalkylamino, azatricycloalkylamino or dicycloalkylamino. The compounds are useful as anti-inflammatory and anti-allergy agents.

REFERENCES:
patent: 3392194 (1968-07-01), Waring
patent: 3624143 (1971-11-01), Shen et al.
patent: 3652646 (1972-03-01), Leigh et al.
patent: 4534874 (1985-08-01), Steinberg et al.

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