Bicycloalkyl derivatives of prostaglandins: 11-deoxy-PGE.sub.1 a

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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560116, C07C17700

Patent

active

041088921

ABSTRACT:
Novel bicycloalkyl analogues or derivatives of prostaglandin A, E, and F are useful modifiers of smooth muscle activity. The compounds have valuable pharmacological properties as platelet antiaggregating agents and gastric antisecretory agents. The compounds are also valuable pharmacological agents for increasing femoral blood flow and decreasing blood pressure and heart rate.

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