Bicyclo lactone intermediates for prostaglandin analogs

Details Bicyclo lactone intermediates for prostaglandin analogs Bicyclo lactone intermediates for prostaglandin analogs

1972-05-10

1981-12-08

Randolph, John D.

Harness for working animal

560 53, 560 60, 562463, 562470, 424279, 424308, 424317, C07D30783

Patent

active

043049079

ABSTRACT:
Prostaglandin-type compounds with a phenoxy or substituted-phenoxy substituent at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
patent: 3505386 (1970-04-01), Babcock et al.
patent: 3711515 (1973-01-01), Kelly
patent: 3711528 (1973-01-01), Beal et al.
Wadsworth et al., J. Org. Chem., vol. 30, pp. 680 to 685 (1965).
Corey et al., J. Am. Chem. Soc., vol. 92, pp. 397 to 398 (1970).

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