Bicyclic sulfonamide derivatives and process therefor

Details Bicyclic sulfonamide derivatives and process therefor Bicyclic sulfonamide derivatives and process therefor

1988-04-28

1990-02-27

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 12, 560138, 562427, C07C 6974

Patent

active

049048198

ABSTRACT:
Bicyclic sulfonamide derivatives represented by the formula: ##STR1## (wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 is lower alkyl, aralkyl, or aryl which may be substituted by lower alkyl, alkoxy, acetoxy, hydroxy, halogen, nitro or phenyl; and the wavy line indicates R or S configuration or their mixture) or their salt being used as antithrombotic, antivasoconstricting, and antibronchoconstricting drugs and the process therefor.

REFERENCES:
patent: 3449346 (1969-06-01), Aumuller
patent: 3706790 (1972-12-01), Sprague et al.
patent: 3806534 (1974-04-01), Feit et al.
patent: 3992440 (1978-11-01), Werner
patent: 4389413 (1983-06-01), Homanka
patent: 4443477 (1984-04-01), Witte et al.

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