Bicyclic sulfonamide derivatives

Details Bicyclic sulfonamide derivatives Bicyclic sulfonamide derivatives

1989-03-23

1990-12-11

Brust, Joseph Paul

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

546293, 560 10, 560119, 562427, 562501, C07C31110, C07C31113, C07C31120

Patent

active

049768913

ABSTRACT:
Bicyclic sulfonamido derivatives represented by the formula: ##STR1## wherein R.sub.1 is a hydrogen or lower alkyl; R.sub.2 is an alkyl, substituted or unsubstituted arly, aralkyl or hetelocycle; R.sub.3 is hydrogen or methyl; X is an alkylene or alkenylene which may be substituted by a fluorine atom or atoms and may contain an oxygen, sulfur and/or phenylene in the chain; Y is straight or branched alkylene or alkeneylene, oxygen, or sulfur; m is 0 or 1; and n is 0, 1 or 2, or their salt, said derivatives being useful as antithrombotic, anti-vasoconstricting, and anti-bronchoconstricting drugs.

REFERENCES:
patent: 3988362 (1976-10-01), Bernauer et al.
patent: 4389413 (1983-06-01), Hamanaka et al.
patent: 4458091 (1984-07-01), Jones et al.
patent: 4647585 (1987-03-01), Loots et al.
patent: 4654357 (1987-03-01), Nakane
Watanabe, et al.; C. A., 108:111866E (1988).

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