Bicyclic substituted hexahydrobenz[e]isoindole .alpha.-1 adrener

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514259, 514265, 514262, 514258, 548427, 544255, 544256, 544257, 544258, 544262, 544268, 544276, 544278, 544279, 544280, 544284, C07D40302, C07D40314, A61K 31505, A61K 3140

Patent

active

055211810

ABSTRACT:
The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.

REFERENCES:
patent: 5420128 (1995-05-01), Kiyokawa et al.

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