Bicyclic spirohydantoin CGRP receptor antagonists

Details Bicyclic spirohydantoin CGRP receptor antagonists Bicyclic spirohydantoin CGRP receptor antagonists

2006-11-14

2011-12-06

Andres, Janet L. (Department: 1622)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S018000

Reexamination Certificate

active

08071771

ABSTRACT:
Compounds of formula I:(wherein variables A1, A2, A3, A4, A5, A6, A7, B, E1, E2, E3, E4, E5, G1, G2and R6are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

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