Bicyclic pyrimidine compounds and therapeutic use thereof

Details Bicyclic pyrimidine compounds and therapeutic use thereof Bicyclic pyrimidine compounds and therapeutic use thereof

2005-10-04

2005-10-04

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S323000, C544S324000, C544S325000

Reexamination Certificate

active

06951866

ABSTRACT:
1. A pyrimidine derivative of the formula (1) or a salt thereof;has an inhibitory activity of production of Th2 type cytokines such as IL-4, IL-5, etc., and is useful as an therapeutic agent for allergic diseases, autoimmune diseases such as systemic lupus erythemathosus, etc., and acquired immunodeficiecy syndrome (AIDS) and so on.

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Elslager et al., Journal of Medicinal Chemistry, vol. 17, No. 1, pp. 75-100 (1974).
Modest et al., Chemical Abstract 63:5639f, (1965).
Ross et al., Chemical Abstract 54:6742b, (1960).

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