Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-08-09
2011-08-09
Kosack, Joseph (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S338000, C514S256000, C514S333000, C514S253090, C514S234500, C514S322000, C514S303000, C544S364000, C544S133000, C548S201000, C546S269700, C546S167000, C546S199000, C546S119000
Reexamination Certificate
active
07994202
ABSTRACT:
A nitrogen-containing bicyclic heterocyclic compound represented by the following formula (1) is provided. When the compound or a salt thereof is administered to a human being or an animal, the compound has a strong antagonistic action against EP1 receptors, and is useful, for example, as an active ingredient of a medicine for the prevention and/or treatment of overactive bladder. The compound is also useful as an active ingredient of a medicine for the prevention and/or treatment of symptoms such as frequency urinary, urinary urgency, or urinary incontinence.
REFERENCES:
patent: 7226941 (2007-06-01), Park et al.
patent: 7241791 (2007-07-01), Steffan et al.
patent: 7304073 (2007-12-01), Chadwick et al.
patent: 7446222 (2008-11-01), Bit et al.
patent: 7678823 (2010-03-01), Slade et al.
patent: 2002/0137746 (2002-09-01), Carl et al.
patent: 2004/0167127 (2004-08-01), Steffan et al.
patent: 2005/0020646 (2005-01-01), Newgreen et al.
patent: 2005/0187276 (2005-08-01), Park et al.
patent: 2006/0111421 (2006-05-01), Chadwick et al.
patent: 2006/0205751 (2006-09-01), Lee et al.
patent: 2006/0235057 (2006-10-01), Bit et al.
patent: 2007/0225349 (2007-09-01), Steffan et al.
patent: 2008/0207708 (2008-08-01), Bit et al.
patent: 2008/0249135 (2008-10-01), Slade et al.
patent: 2008/0275053 (2008-11-01), Giblin et al.
patent: 2010/0120749 (2010-05-01), Page et al.
patent: 00/69465 (2000-11-01), None
patent: 02/15902 (2002-02-01), None
patent: 2004/031159 (2004-04-01), None
patent: 2004/039753 (2004-05-01), None
patent: 2004/083185 (2004-09-01), None
patent: 2005/010534 (2005-02-01), None
patent: 2005/030121 (2005-04-01), None
patent: WO 2006041874 (2006-04-01), None
patent: WO 2007115306 (2007-10-01), None
patent: 2008/006790 (2008-01-01), None
patent: 2008/006793 (2008-01-01), None
patent: 2008/006794 (2008-01-01), None
patent: 2008/006795 (2008-01-01), None
patent: 2008/040753 (2008-04-01), None
patent: 2008/054749 (2008-05-01), None
patent: WO 2008049875 (2008-05-01), None
Freeman et al. Best Practice & Research Clinical Obstetrics and Gynaecology, 2005, 19, 529-841.
E. Ann Hallinan et al., “2,4-Disubstituted Oxazoles and Thiazoles as Latent Pharmacophores for Diacylhydrazine of SC-51089, a Potent PGE2Antagonist” Bioorganic & Medicinal Chemistry, vol. 9, pp. 1-6, 2001.
Adrian Hall et al., “Novel Methylene-Linked Heterocyclic EP1Receptor Antagonists” Bioorganic & Medicinal Chemistry Letters, vol. 18, pp. 1592-1597, 2008.
Adrian Hall et al., “Discovery of a Novel Indole Series of EP1Receptor Antagonists by Scaffold Hopping” Bioorganic & Medicinal Chemistry Letters, vol. 18, pp. 2684-2690, 2008.
A. Ziganshin et al., “Studying the Efficacy of a Series of Quinoxaline and Azolo[a(b)]quinoxaline Derivatives as P2X Receptor Antagonists” Eksp, Klin. Farmakol., vol. 68, No. 1, pp. 56-60, 2005, along with an English language abstract thereof.
U.S. Appl. No. 12/502,529 to Atobe et al., entitled “Nitrogen-Containing Heterocyclic Compounds,” filed Jul. 14, 2009.
Li et al., “Design, Synthesis, and Biological Evaluation of Antiviral Agents Targeting Flavivirus Envelope Proteins,”J. Med. Chem., vol. 51, No. 15, pp. 4660-4671, 2008.
U.S. Office Action that issued with respect to U.S. Appl. No. 12/502,529, mailed Aug. 2, 2010.
U.S. Office Action that issued with respect to U.S. Appl. No. 12/502,529, mailed Jan. 6, 2011.
American Urogynecologic Society. Bladder Control Problems: Prevention. Published May 2008. Accessed Dec. 30, 2010. <http://www.mypelvichealth.org/TreatmentPrevention/BladderControlProblems/Prevention/tabid/115/Default.aspx>.
Atobe Masakazu
Morimoto Akifumi
Naganuma Kenji
Asahi Kasei Pharma Corporation
Coughlin Matthew
Greenblum & Bernstein PLC
Kosack Joseph
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