Bicyclic intermediates for excitatory amino acid receptor antago

Details Bicyclic intermediates for excitatory amino acid receptor antago Bicyclic intermediates for excitatory amino acid receptor antago

1993-10-18

1996-02-13

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548251, 548253, C07D20952

Patent

active

054912415

ABSTRACT:
This invention provides novel bicyclic compounds which are useful as excitatory amino acid receptor antagonists and in the treatment of neurological disorders. This invention also provides intermediates useful in the synthesis of excitatory amino acid antagonists.

REFERENCES:
patent: 4691022 (1987-09-01), Henning et al.
patent: 4999370 (1991-03-01), Ruger et al.
Zimmerman, D. M. et al, Trends in Medicinal Chemistry '90, Oxford (1991), pp. 145-151.
Watkins, J. C., Can. J. Physiol. Pharmacol., (1991), vol. 69, pp. 1064-1075.
Rogawski, M. A., Drugs, (1992) vol. 44, No. 3, pp. 279-292.
Ornstein, P. L. et al., J. Med. Chem., (1991), vol. 34, pp. 90-97.

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