Bicyclic heterocycles useful as selective androgen receptor...

Details Bicyclic heterocycles useful as selective androgen receptor... Bicyclic heterocycles useful as selective androgen receptor...

2007-02-01

2009-12-01

Anderson, Rebecca L (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S361000

Reexamination Certificate

active

07626036

ABSTRACT:
The present invention is directed to novel bicyclic heterocycles, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

REFERENCES:
patent: 2003/0055094 (2003-03-01), Sun et al.
patent: 55043057 (1980-03-01), None
patent: WO 03/096980 (2003-11-01), None
Basaria, S. et al.: “Anabolic-Androgenic Steroid Therapy in the Treatment of Chronic Diseases”; The J. of Clin. Endocrinology & Metabolism (2001) 86(11): 5108-5117.
Newling, D.W.W.: “Anti-androgens in the treatment of prostate cancer”; British J. of Urology (1996) 77: 776-784.
Shahidi, N.T. MD: “A Review of the Chemistry, Biological Action, and Clinical Applications of Anabolic-Androgenic Steroids”; Clinical Therapeutics (2001) 23(9): 1355-1390
Zhang, X. et al.: “Synthesis and SAR of novel hydantoin derivatives as selective androgen receptor modulators”; Elsevier Bioorganic & Med. Chem. Ltrs. (2006) 15: 5763-5766.
PCT International Search Report for International Application No. PCT/US2007/061438 dated Jun. 15, 2007.

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