Bicyclic heterocycles, the preparation thereof, and their use as

Details Bicyclic heterocycles, the preparation thereof, and their use as Bicyclic heterocycles, the preparation thereof, and their use as

1999-02-02

2000-09-05

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514314, 514367, 514394, 5483061, 5483097, C07D20918, C07D23516, C07D41306, C07D40112, C07D30701, C07D26356, A61K 314184

Patent

active

061145327

ABSTRACT:
The present invention relates to 5-membered heterocyclic condensed benzoderivatives of formula ##STR1## wherein R.sub.a to R.sub.c, A, X and Y are defined as in claim 1, the tautomers, stereoisomers, mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable properties.
The compounds of the above formula I wherein R.sub.c denotes a cyano group are valuable intermediates for preparing the other compounds of formula I, and the compounds of the above formula I wherein R.sub.c denotes one of the following amidino groups and the tautomers and stereoisomers thereof have valuable pharmacological properties, particularly an antithrombotic activity.

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