Bicyclic heterocycles, pharmaceutical compositions...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S253000, C544S283000, C514S266100

Reexamination Certificate

active

07863281

ABSTRACT:
The present invention relates to bicyclic heterocycles of general formulawhereinRa, Rb, Rc, A, B, C, D, E and X are defined as in claim1, the tautomers, the stereoisomers, the mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, particularly tumoral diseases, as well as benign prostatic hyperplasia (BPH), diseases of the lungs and respiratory tract, and the preparation thereof.

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