(Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotrien

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514302, 514367, 514375, 514382, 514414, 546114, 546115, 548159, 548217, 548221, 548252, 548253, 548454, A61K 31435, A61K 31425, C07D49504, C07D27504

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053088506

ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

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