Bicyclic guanidine derivatives and therapeutic uses thereof

Details Bicyclic guanidine derivatives and therapeutic uses thereof Bicyclic guanidine derivatives and therapeutic uses thereof

2002-02-27

2009-02-17

Richter, Johann R. (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S302000, C514S303000, C514S367000, C514S375000, C514S394000, C546S114000, C546S115000, C546S176000, C548S152000, C548S215000, C548S309700, C548S469000, C549S049000, C549S462000

Reexamination Certificate

active

07491733

ABSTRACT:
The invention relates to compounds of general formula (I), in which A, X, Y and R1 are defined in Claim1. These compounds may be used in the treatment of pathologies associated with insulin resistane syndrome.

REFERENCES:
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patent: 3700697 (1972-10-01), Bailey
patent: 3855242 (1974-12-01), Chapman et al.
patent: 4260628 (1981-04-01), Jonas et al.
patent: 1502346 (1968-02-01), None
patent: P9102206 (2000-01-01), None
Chapman et al. Pharmacologically active benzo[b]thiophen derivatives. Analogues of tryptamine and heteroauxin Journal of the Chemical Society Section C: Organic Chemistry 1969, 12, 1612-1616.
N.B. Chapman et al : “Pharmacologically active benso'b!thionphen deriivatives. Analogues of tryptamine and heteroauxin” Journal of the Chemical Society, Section C: Organic Chemistry, No. 12, 1969, pp. 1612-1616.
K. S. Sharma et al.; “Condensed Heterocyclics: Part XVI-Synthesis of N-Substituted 4-Bromo-2-guandinomethylbenzo[b]thiophenes”; Indian Journal of Chemistry: vol. 23B, Jan. 1984; pp. 38-41.

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