Bicyclic-fused pyridines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546111, A61K 3144, C07D22116

Patent

active

060637889

ABSTRACT:
Bicyclic-fused pyridines are prepared by introducing the appropriate side chain by reaction of the corresponding aldehydes with the aid of Wittig or Grignard reagents. The bicyclic-fused pyridines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosi.

REFERENCES:
patent: 4814346 (1989-03-01), Albert et al.
patent: 5006530 (1991-04-01), Angerbauer et al.
patent: 5169857 (1992-12-01), Angerbauer et al.
patent: 5254565 (1993-10-01), Meguro et al.
Petrow, et al.: "New Synthesis of Heterocyclic compounds, Part X, Azafluorenones" Journal of the Chemical Society, 1949, pp. 2134-2137, XP002049743.
Dinchuck, Hart, Gonzales, Karmann, Schmidt, Wirak, BBA (1995) vol. 1295, p. 301.

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