Bicyclic fibrinogen antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

540593, 540594, C07D22316, A61K 3155

Patent

active

059394129

ABSTRACT:
Compounds of the formula: ##STR1## wherein A.sup.1 to A.sup.5 form a seven-membered ring containing one optionally substituted nitrogen atom;

REFERENCES:
patent: 4297346 (1981-10-01), Rips et al.
patent: 4322436 (1982-03-01), Korosi et al.
patent: 4327026 (1982-04-01), Branca et al.
patent: 4361511 (1982-11-01), Branca et al.
patent: 4377522 (1983-03-01), Branca et al.
patent: 4410520 (1983-10-01), Watthey et al.
patent: 4604389 (1986-08-01), Reiffen et al.
patent: 4737495 (1988-04-01), Bomhard et al.
patent: 4808713 (1989-02-01), Attwood et al.
patent: 4820834 (1989-04-01), Evans et al.
patent: 5008263 (1991-04-01), Cooper et al.
patent: 5017571 (1991-05-01), Hansen et al.
patent: 5059688 (1991-10-01), Effland et al.
patent: 5096900 (1992-03-01), George et al.
patent: 5149699 (1992-09-01), Ellinboe et al.
patent: 5241065 (1993-08-01), Berger et al.
patent: 5250679 (1993-10-01), Blackburn et al.
patent: 5403836 (1995-04-01), Blackburn et al.
patent: 5438118 (1995-08-01), Callahan et al.
patent: 5470849 (1995-11-01), Callahan et al.
patent: 5565449 (1996-10-01), Blackburn et al.
patent: 5663166 (1997-09-01), Blackburn et al.
patent: 5674863 (1997-10-01), Blackburn et al.
patent: 5674865 (1997-10-01), Blackburn et al.
patent: 5693636 (1997-12-01), Bondinell et al.
Tighneanu et al., Double Cyclisation of Phenyglycine-o-carboxylic Acids-I, Tetrahedron, 36, 1385 (1980).
Callahan et al., Peptide Chemistry 1992: Proceeding of the 2nd Japanese Symposium on Peptides Chemistry, p. 495 (1993).
Ku et al., J. Am. Chem. Soc., 115, 8861 (1993).
Tidwell et al., Thrombosis Research, vol. 19, pp. 339-349 (1980).
Ku et al., J. Med. Chem., 38(1), pp. 9-12 (1995).
Sternbach, L.H., J. Med Chem., 22, 2 (1979).
Friedinger, R.M., Cholecystokinin and Gastrin Antagonists, Med. Res. Rev., 9, 271 (1989).
Mori et al., New Synthesis of Diazepinone Skeleton Using Palladium Catalyzed Carbonylation, Heterocycles, 16 (1981).
Muller et al., Synthese von 1, 2-annelierten 1, 4-Benzodiazepinen und 4, 1-Benzoxazepinen, Helv. Chim. Acta, 65, 2118 (1982).
Heindel et al., Synthesis, Transformation and General Pharmacologic Activity in 1,4-Benzodiazepin-3,5-Diones, J. Med. Chem., 14, 1233 (1971).
Pauwells et al., Potent and Selective Inhibition of HIV-1 Replication in vitro by a Novel Series of TIBO Derivatives, Nature, 343, 470 (1990).
Nichols et al., J. Pharm. Exp. Ther., 270, 614 (1994).
Coller, Coronary Artery Disease, 3, 1016 (1992).
Topol et al., Thrombosis and Haemostasis, 70, 94 (1993).
Nichols et al.,TIPS, 13, 413 (Nov. 1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Bicyclic fibrinogen antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bicyclic fibrinogen antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic fibrinogen antagonists will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-314945

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.