Bicyclic diterpene PAF antagonist compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514766, 549457, 549459, 585360, C07D30777, A61K 3134

Patent

active

053387589

ABSTRACT:
Four bicyclic terpenes isolated from a culture broth of Phoma sp SCF0592, ATCC 74077, pharmaceutical compositions containing them and their use as PAF antagonists to treat allergic and inflammatory diseases are disclosed.

REFERENCES:
Karlsson, B., et al. Tetrahedron (1978) vol. 34 pp. 2349-2354.
Chem Abstracts (1992) 116: 57549d-Corresponds to Japanese Kokai JP 03,216,197 (91,216,197).

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