Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2007-02-20
2007-02-20
Kumar, Shailendra (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C514S613000, C514S623000, C568S338000, C568S361000, C568S374000
Reexamination Certificate
active
11151624
ABSTRACT:
Bicyclic amide derivatives of formula (I) or tautomers or pharmaceutically acceptable salts thereof or both are provided:Also provided are processes for preparing the bicyclic amide derivatives as well as pharmaceutical compositions containing the same and therapeutic uses. The bicyclic amide derivatives are useful for treating a variety of conditions associated with the abnormal modulation of one or more Kv1.1 voltage-gated potassium channels.
REFERENCES:
patent: 3746765 (1973-07-01), Ruschig et al.
patent: 4134987 (1979-01-01), Huppatz
patent: 4324912 (1982-04-01), Klemarczyk et al.
patent: 2003/0024001 (2003-01-01), Wyeth
patent: 27 01 091 (1977-07-01), None
patent: 44 17 474 (1995-11-01), None
patent: 56008327 (1981-01-01), None
patent: 63010781 (1988-07-01), None
patent: 02157266 (1990-06-01), None
C. Oliver Kappe et al., J. Org. Chem., 58, 3361-3367 (1993).
K.J. Angelides et al., The Journal of Biological Chemistry, 258(19), 11948-11957 (1983).
G. Shi et al., Neuron, 16, 843-852 (1996).
J. Xu et al., Trends Cardiovascular Medicine, 8(5), 229-234 (1998).
S. Smart et al., Neuron, 20, 809-819 (1998).
S.M. Zuberi et al., Brain, 122, 817-825 (1999).
V.S. Velezheva et al., Zhurnal Organicheskoi Khimii, 14(8), 1712-1723 (1978).
J. H. Nelson et al., Synth. React. Inorg. Met.-Org. Chem., 9(5), 435-444 (1979).
D. Browne et al., Nature Genetics, 8, 136--140 (1994).
J. Rettig et al., Nature, 369, 289-294 (1994).
E. Isacoff et al., Nature, 353, 86-90 (1991).
J. Rho et al., Dev. Neurosci., 21, 320-327 (1999).
O. Pongs et al., Annals New York Academy of Sciences, 868, 344--355 (1999).
K. Uehara et al., Bullentin of the Chemical Society of Japan, 49(5), 1447-1448 (1976).
S. Yamaguchi et al., Epilepsy Res., 11, 9-16 (1992).
C. Miller, Science, 252, 1092-1096 (1991).
W. Zagotta et al., Science, 250-568-571 (1990).
J. Butterworth et al., Anesthesiology, 72, 711-734 (1990).
E. Sledziewska et al., Roczneki Chemn Ann. Soc. Chim. Polonorum, 49, 733-742 (1975).
H. Kolb, Rev. Physiol. Biochem. Pharmacol., 115, 51-91 (1990).
A. Davies et al., J. Chem. Soc., 1479-1483 (1968).
B. Barsoum et al., Indian Journal of Chemistry, 25A, 694-695 (1986).
J. Nelson et al., Fundam. Res. Homogeneous Catal. 3, 921-939 (1979).
M. Kamal et al., Dirasat. [Ser.]: Nat. Sci. (Univ. Jordan), 7, 33-40 (1980).
P. Schwartzkroin et al., Brain Research, 185, 169-181 (1980).
N. Singh et al., Nat. Genet., 18, 25-29 (1998).
K. Rhodes et al., The Journal of Neuroscience, 17(21), 8246-8258 (1997).
G. Gandolfo et al., Brain Research, 495, 189-192 (1989).
J. Bidard et al., Brain Research, 495, 45-57 (1989).
J. Kenney et al., J.C.S. Chem. Comm., 690-691 (1973).
M. Madeja et al., European Journal of Neuroscience, 9, 39-395 (1997).
D. Prince, Ann. Rev. Neurosci., 1, 395-415 (1978).
M. Tsaur et al., Neuron, 8, 1055-1067 (1992).
S. Heinemann et al., Journal of Physiology, 493(3), 625-633 (1996).
SM Zuberi et al., Epilepsia, 38(3), 104 (1997).
C. Biervert et al., Science, 279, 403-406 (1998).
C. Charlier et al., Nature Genetics, 18, 53-55 (1998).
S. Zini et al., Neuroscience Letters, 153, 202-205 (1993).
L. Hevesi et al., Bulletin De La Societe Chimique De France, 11, 3971-3975 (1970).
L. Hevesi et al., Bulletin De La Societe Chimique De France, 11, 4066-4072 (1971).
G. Kollenz et al., Z. Naturforsch, 31b, 1511-1514 (1976).
M.V. Rubtsov, Khim. Geterotsikl, Socdin, 10, 1432-1435 (1976).
E. Ziegler et al., Synthesis, 11, 679-680 (1973).
A. Kettrup et al., Z. Anal. Chem. 269, 118-121 (1974).
Macias et al., Zhurnal Organicheskoi Khimii, 18(7), 1386-1390 (1982); translation attached Journal of Organic Chemistry of the USSR, 18, 1205-1208 (1982).
M. Ocana et al., European Journal of Pharmacology, 500, 203-219 (2004).
Childers Wayne E.
Kim Callain Y.
Podlesny Edward J.
Wu Jerome C.
Hild Kimberly R.
Kumar Shailendra
Wyeth
LandOfFree
Bicyclic derivatives that modulate voltage-gated potassium... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bicyclic derivatives that modulate voltage-gated potassium..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic derivatives that modulate voltage-gated potassium... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3874747