Bicyclic compounds capable of inhibiting tyrosine kinases of the

Details Bicyclic compounds capable of inhibiting tyrosine kinases of the Bicyclic compounds capable of inhibiting tyrosine kinases of the

1994-12-23

1997-08-05

Wu, Shean C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544253, 544279, A61K 31505, C07D23970, C07D48700

Patent

active

056543077

ABSTRACT:
Novel 4-substituted amino pyrido pyrimidine and 4-substituted amino pyrido pyrimidine inhibitors of epidermal growth factor receptor family of tyrosine kinase are described, as well as pharmaceutical compositions of the same, which are useful in treating proliferative diseases such as cancer, synovial pannus invasion in arthritis, psoriasis, vascular restenosis and angiogenesis and additionally useful in the treatment of pancreatitis and kidney disease as well as a contraceptive agent.

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