Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-10-11
2009-06-23
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S360000, C546S348000, C585S025000
Reexamination Certificate
active
07550467
ABSTRACT:
The present invention discloses compounds of Formula Iwherein V, W, Y, Z, R1, R2, R3, R4, d, m, n, p and r are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes. An illustrative compound is shown below:
REFERENCES:
patent: 2001/0041700 (2001-11-01), Bekkali et al.
patent: WO 02/057233 (2002-07-01), None
patent: WO 03/007888 (2003-01-01), None
patent: WO 03/047568 (2003-06-01), None
patent: WO 2004/037777 (2004-05-01), None
Gu Huizhong
Guo Tao
Hobbs Douglas Walsh
Kalyanaraman Palaiyur S.
Schering Corporation
Willis Douglas M
Wilson James O
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