Bicyclic carbohydrates as antiviral bioactives for the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C549S364000, C549S365000

Reexamination Certificate

active

07098243

ABSTRACT:
Novel bicyclic carbohydrate compounds are effective for the prophylaxis and treatment of diseases caused by infections of the alphaherpesvirinae HSV-1 and HSV-2. The invention includes the compoundwherein X1, X2, and X3are selected from the group consisting of O, N, and S; wherein Y1and Y2are selected from the group consisting of O, N, and S; and wherein Z is selected from the group consisting of F, Cl, and Br, as well as analogs, prodrugs and pharmaceutically acceptable salts thereof, together with pharmaceutical compositions for the prophylaxis and treatment of diseases caused by infections of alphaherpesvirinae.

REFERENCES:
patent: 5753141 (1998-05-01), Siemensmeyer et al.
patent: WO 03/082846 (2003-10-01), None
patent: WO 04/014929 (2004-02-01), None
Exhibit I, search result.
Akanitapichat et al. “1,3-dihydroxyacridone . . . ” CA 133:26483 (2000).
Database CAPLUS on STN, AN 2001:544756. Espinola et al. “Synthetic Flux-Promoting Polyether Modstl: Cation Flux Dependence on Polyoxyethylene Chain Length”, Isreal Journal of Chemistry. 2000, vol. 40, Issue 3-4.

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