Bicyclic carbohydrate compounds useful in the treatment of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S025000, C514S451000, C549S364000, C549S365000

Reexamination Certificate

active

07125853

ABSTRACT:
We describe the use of bicyclic carbohydrates for the treatment of hepatitis C virus infections. Different bicyclic carbohydrates were tested in vitro against DNA-viruses, retro-viruses andFlaviviridaesp., an important family of human and animal RNA pathogens. Significant activity was observed against the bovine viral diarrhea virus (BVDV). As pestiviruses, such as BVDV, share many similarities with hepatitis C virus (HCV), the bicyclic carbohydrates in general and the preferred bicyclic carbohydrates more specifically are expected to be a treatment for hepatitis C viral infections.

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patent: WO 03/082846 (2003-10-01), None
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Database CAPLUS on STN, AN 2001:544756. Espinola et al. “Synthetic Flux-Promoting Polyether Modstl: Cation Flux Dependence on Polyoxyethylene Chain Length”, Isreal Journal of Chemistry, 2000, vol. 40, Issue 3-4.

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