Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2006-02-20
2010-12-28
Chandrakumar, Nizal S (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
C544S117000
Reexamination Certificate
active
07858788
ABSTRACT:
Is to provide a novel compound having an anti-viral activity, particularly a HIV integrase inhibitory activity, and an agent, particularly an anti-HIV agent.A compound represented by the formula:(whereinZ1is NR4(R4is hydrogen, optionally substituted lower alkyl etc.), O or CH2;Z2is optionally substituted lower alkylene or optionally substituted lower alkenylene, each may be intervened by a heteroatom group selected from group consisting O, S, SO, SO2, NR5(R5is selected independently from the same substituent group of R4) —N═ and ═N—;R1is hydrogen or lower alkyl;X is a single bond, a heteroatom group selected from O, S, SO, SO2and NH, or lower alkylene or lower alkenylene each may be intervened by the heteroatom group;R2is optionally substituted aryl;R3is hydrogen, halogen, hydroxy, optionally substituted alkyl group etc.)
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Kawasuji Takashi
Taoda Yoshiyuki
Yoshida Hiroshi
Chandrakumar Nizal S
Shionogi & Co. Ltd.
Wenderoth , Lind & Ponack, L.L.P.
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