Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2010-05-04
2011-11-22
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S248000, C514S258100, C514S321000, C544S235000, C544S237000, C544S278000, C546S196000, C546S197000, C546S205000, C546S207000, C546S214000
Reexamination Certificate
active
08063070
ABSTRACT:
The present invention of compounds of formula (I)a stereochemically isomeric form thereof, an N-oxide form thereof or a pharmaceutically acceptable acid addition salt thereof. Processes for preparing said products, formulations comprising said products and their use as a medicine are disclosed, in particular for treating conditions which are related to impairment of gastric emptying.
REFERENCES:
patent: 4711703 (1987-12-01), Wright et al.
patent: 4722630 (1988-02-01), Fang
patent: 4853394 (1989-08-01), King et al.
patent: 4910312 (1990-03-01), Pavia
patent: 5130312 (1992-07-01), Van Daele et al.
patent: 5185335 (1993-02-01), Van Daele et al.
patent: 5262418 (1993-11-01), Van Daele et al.
patent: 5374637 (1994-12-01), Van Daele et al.
patent: 5948794 (1999-09-01), Van Daele et al.
patent: 6127379 (2000-10-01), King et al.
patent: 6172062 (2001-01-01), Clark et al.
patent: 6452013 (2002-09-01), Bosmans et al.
patent: 6635643 (2003-10-01), Bosmans et al.
patent: 7790750 (2010-09-01), Bosmans et al.
patent: 0332171 (1989-08-01), None
patent: 0445862 (1991-09-01), None
patent: 0299566 (1994-09-01), None
patent: 0309043 (1994-11-01), None
patent: 0389037 (1995-09-01), None
patent: 0774460 (1997-05-01), None
patent: 196054 (1988-09-01), None
patent: WO 9303725 (1993-03-01), None
patent: WO 9305038 (1993-03-01), None
patent: WO 9316072 (1993-08-01), None
patent: WO 9408995 (1994-04-01), None
patent: WO 9410174 (1994-05-01), None
patent: WO 9633186 (1996-10-01), None
patent: WO 9711054 (1997-03-01), None
patent: WO 9729739 (1997-08-01), None
patent: WO 9923654 (1999-05-01), None
Fancelli, D., et al. Serotoninergic 5-HT3and 5-HT4Receptor Activities of Dihydrobenzofuran Carboxylic Acid Derivatives, Bioorganic & Medicinal Chemistry Letters, 1996, vol. 6, No. 3, pp. 263-266.
Gaster, et al., “1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate Hydrochloride: A Highly Potent and Selective 5-HT4Receptor Antagonist Derived from Metoclopramide,” Journal of Medicinal Chemistry, Dec. 1993, 36(25), 4121-4123.
Itoh et al. “Synthesis and . . .” CA 131:286384 (1999).
Lewis, N., et al., Diacetoxypiperidinium Analogs of Acetylcholine, Journal of Medicinal Chemistry, Feb. 1973, vol. 16, Issue 2, pp. 156-159.
Meulemans et al., “Use of 5HT4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors”, 1998, 3 pages.
Patani et al., “Bioisosterism: A Rational Approach in Drug Design”, Chem. Rev. May 1996, 96, 3147-3176.
Prieto et al. “Piperidinylmethyl . . .” CA 129:316144 (1998).
SB205800 Dialog file 452, assess No. 00199407 (1993).
Van Daele et al. “N-3-hydroxy . . .” CA 123:143904 (1995).
Bosmans Jean-Paul Rene Marie Andre
De Cleyn Michel Anna Jozef
Surkyn Michel
Chang Celia
Janssen Pharmaceutica N.V.
Woodcock & Washburn LLP
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